J. Keith Thompson, DO, RVT, FACOS

With more than 18 years of vein experience, Dr. J. Keith Thompson is a board-certified vascular surgeon and founder of the Vein Institute where he specializes in providing the most advanced treatments for patients with complex venous issues. Prior to founding the VI he played a crucial role in the state in developing minimally invasive treatments for several vascular problems. Dr. Thompson has published research in numerous vascular and surgical journals. In his free time, he enjoys being at home with his wife, their two children, and their four (!) dogs in south Mississippi.



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Education and Training

Dr. Thompson earned his undergraduate degree at Ole Miss in political science and chemistry before obtaining his medical degree from the Kansas City University of Medicine. Following this, Dr. Thompson completed surgery internship in Fort Worth, Texas followed by surgery residency at Ohio University in Columbus Ohio. After completing residency and being board certified in general surgery, he completed a two-year vascular surgery fellowship at the University of Cincinnati. During residency and fellowship he also participated in advanced vascular training at the Ohio State University and the Cleveland Clinic Foundation. Dr. Thompson is a board-certified vascular surgeon and has performed over 10,000 vascular surgeries and vein procedures. He has given vascular presentations at several conferences nationwide and has served as a clinical professor helping train medical students, residents, and fellows. He is a member of several prestigious vein societies and also serves on committees of the American Venous Forum.

Professional Memberships

Dr. Thompson is a member of numerous medical societies, a few of which include:

  • American Venous Forum
  • Society for Vascular Surgery
  • Society for Clinical Vascular Surgery
  • American Society for Laser Medicine and Surgery
  • Vascular and Endovascular Surgery Society
  • American Vein and Lymphatic Society
  • Society for Vascular Ultrasound
  • American Board of Venous and Lymphatic Medicine

Additional Info

Dr. Thompson has published research in several distinguished vascular journals including assisting in key research in the areas of major vascular trauma. Among these is one of the landmark papers that helped define how major aortic injuries are to be managed in the era of modern minimally invasive vascular technologies, specifically endovascular therapy. This paper alone has been cited nearly 100 times in other major vascular research articles and has played a pivotal role in changing how this arterial injury is managed not only in the US but internationally. Dr. Thompson performed the first vascular surgery of this type in the state of Mississippi in 2005 and later published the first paper in the state that described the technique which was published in the Journal of the Mississippi State Medical Association. This has since become the standard of care in this area of vascular management. Prior to Dr. Thompson’s first case of this type in Mississippi, aortic injuries like this had to be fixed with a complex and risky 6-hour operation that many patients didn’t survive which had an average blood loss of more than 4 quarts. The new minimally invasive procedure can be done in 30 minutes and typically causes less than 5ml of blood loss. This represents a major paradigm shift in how vascular surgeries like this are performed and also requires systems within hospitals to be updated and improved as well.

Dr. Thompson also performed extensive research in the area of blunt injury to the kidney arteries that sometimes occurs in severe car/motorcycle accidents. While a resident in surgery at the busiest Level I trauma center in Ohio he noticed a pattern of vascular injury to the kidney vessels that, at the time, did not have a specific treatment algorithm. With the help of one of his surgery mentors, he was able to publish this research which has since been cited numerous times in the world literature and has helped define how traumatic injuries to kidney vessels can be managed. While training in Columbus, Ohio he was featured in Season 1 of the Discovery Channel trauma surgery reality TV series “The Critical Hour”.

Dr. Thompson has given lectures and numerous vascular presentations at conferences in Chicago, Dallas/Ft Worth, Cincinnati, Miami, Bethesda, New York and others and has participated in training medical students, residents, and fellows.


Thompson JK, Hatten LH. Endovascular repair of blunt traumatic thoracic aortic transection in patients who are not candidates for the gore TAG device. JMSMA 2007;47:355-7.

Thompson JK, Reed AB, Giglia JS. Novel endovascular treatment of blunt thoracic aortic trauma with a self-expanding stent lined with aortic extender cuffs. Ann Vasc Surg 2006;20:271-3.

Reed AB, Thompson JK, Crafton CJ, et al. Timing of endovascular repair of blunt traumatic thoracic aortic transections. J Vasc Surg 2006;43:684-8.

Thompson JK, Reed AB, Crafton CJ, et al. Endovascular fenestration for relief of chronic mesenteric ischemia from chronic type B aortic dissection. Ann Vasc Surg 2006;20:518-20.

Chow SJ, Thompson JK, Hartman JF. A 10-year review of blunt renal artery injuries at an urban level I trauma center. Injury 2009;40:844-50.

Thompson JK, Strunk RS, Giglia JS. Bilateral obturator bypass for combined aortic and femorofemoral graft infection. J Vasc Surg 2006;44:888.

Thompson JK, Edwards JD. Supracondylar process of the humerus causing brachial artery compression and digital embolization in a fast-pitch softball player. Vascular and Endovascular Surgery 2005;39(5):445-8

Giglia JS, Thompson JK. Repair of a thoracoabdominal aortic aneurysm in the presence of a left-sided inferior vena cava. J Vasc Surg 2004;40:161-3.

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6169 U.S. 98 Ste 30

Hattiesburg, MS 39402

Call: 601-336-8368

Trusted, Proven

What a wonderful place. I'm truly happy I went to see Dr Thompson. He closed an ugly feeder vein that has been my shame for several years. I can't wait for shorts and swimsuit weather. And all of his staff are extra sweet and caring.  It was an excellent experience all the way around. I highly recommend the Vein Institute! You won't be disappointed.

S.H. Other

The Doctor and associates were very knowledgeable and friendly.

F.L Other

Very well pleased with Dr. Thompson and all his staff. Would recommend him highly.

M.I Other

Very pleased with the procedures so far.

S.A Other

All the staff are super friendly. My wait time was minimal, and my appointment went very smooth.

G.R Other


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